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Dr. D.S. Merchant's Articles in Psychology

  • Worst Menopause Symptoms May Start in Brain
    "This is an important new concept: Menopause doesn't just originate in the ovary, but also in the brain," said Laura Goldsmith, a professor of obstetrics and gynecology and women's health at the New Jersey Medical School of the University of Medicine and Dentistry of New Jersey.
  • Study Finds Menopause Symptoms Can Be Predicted
    The authors of this study measured ovarian volume with transvaginal ultrasound, then looked at the relationship between ovarian volume -- ovaries shrink as a woman ages -- and number of eggs. They then applied mathematical and computer models to predict menopause.
  • Hoodia Gordonii Helps you Lose Weight
    Hoodia gordonii looks like a cactus, but it's actually a succulent from the Kalahari Desert in southern Africa. Bushmen from the area have been using hoodia for centuries to help ward off hunger during long trips in the desert.
  • The Clinical Approach to Acid-Base Disorders
    Methods to Interconvert pH and [H+]: The 0.1 pH Change Rule:
    PH Conversion Factor [H+] nmol/L
    6.90 100 / 0.8 125
    7.00 100 100
    7.10 100 X 0.8 80
    7.20 100 X 0.8 X 0.8 64
  • Pulmonary Function Testing
    Pulmonary Function Issues Related to Measured Values:
    • Overinflation of Lungs
    – Emphysema - COPD - Permanently
    – Asthma - Acutely
    • ? RV + Ratio RV/TLC
    • FEV1/ FVC ratio falls below 80% - Also flow rates fall
    – With age (lungs less compliant)
    – Falls with obstructive diseases; e.g. asthma/bronchitis
    • Asthma - obstructive disease ? increased collapsing force of large airways
    – obstruction to expiratory flow ? lung volume
    – bronchodilators may return flow to normal
    • Early COPD - characterized by irreversible ? in small airway resistance that reduces expiratory flow
    – not very responsive to dilators
    • Severe COPD - ? small & large airway resist
    – severe flow limitations – bronchodilators ? little help
    – chronic bronchitis and emphysema
    • Emphysema - loss of elastic recoil ? ? small airway collapse during expiration, thereby ? resistance
    – Max Expiratory Flow ?
    – Bronchodilators have no effect
    – ? FRC + TLC
  • Respiratory Disease and Lung Function
    Data Collection:
    • Questionnaire data were collected by trained interviewers who gathered information on race/ethnicity, medical history, socioeconomic status, use of medication, and smoking history.
    • Participants were also asked whether they had taken any of the following pain medications in the last month and, if so, how often they had used each:
    aspirin (including Anacin, Bufferin, Ecotrin, Ascriptin, or Midol), acetaminophen (including Tylenol, Anacin-3), and ibuprofen (including Advil, Nuprin, Medipren).
  • Hyponatremia by eHealthGuide.info
    Hyponatremia:
    Plasma Na < 135meq /L
    • Almost always due to •ADH Secretion
    • Appropriate
    • Inappropriat
    • One Exception: Primary Polydipsia • supression of ADH Secretion BUT still overwhelms kidney’s diluting ability • Free water retention & Hyponatremia

    Epidemiology of Hyponatremia:
    Hyponatremia is among the most common electrolyte disorders encountered in clinical medicine, with an incidence of 0.97% and a prevalence of 2.48% in hospitalized adult patients when plasma [Na+ ] concentration below 130 mEq/L is the diagnostic criterion.

    Clinical Manifestations:
    • < 125 mEq/l •
    • Malaise - Muscle cramps
    • Nausea, Vomiting, Headache
    • Hypotension – Tachycardia

    • < 110 mEq/L •
    • Confusion, convulsions, coma
  • Guillain Barre Syndrome
    Me score on the Glasgow Outcome Scale at eight weeks (a score of 5, indicating a favorable outcome, vs. a score of 1 to 4, indicating an unfavorable outcome).
    • The mortality rate among adults with acute bacterial meningitis and the frequency of neurologic sequelae among those who survive are high, especially among patients with pneumococcal meningitis.
  • Drug Resistance In Tuberculosis
    Inadequate Prescribing Practice:
    • In 1995 25% of new cases of TB were initially treated with 2-3 drugs regimen
    • 2 Surveys by AKUH among GP & Interns
    • Once resistance develops, prescribing errors, usually by inexperienced physicians can exacerbate situation.
    • Review of patients referred to National Jewish Hospital (Denver) for management of complex MDR-TB documented an average of 3.93 prescribing errors per patient.
  • Dexamethasone in Adults with Bacterial Meningitis
    Methods:
    • a prospective, randomized, double-blind, multicenter trial of adjuvant treatment with dexamethasone, as compared with placebo, in adults with acute bacterial meningitis.
    • Dexamethasone (10 mg) or placebo was administered 15 to 20 minutes before or with the first dose of antibiotic and was given every 6 hours for four days.
    • The primary outcome measure was the score on the Glasgow Outcome Scale at eight weeks (a score of 5, indicating a favorable outcome, vs. a score of 1 to 4, indicating an unfavorable outcome).
    • The mortality rate among adults with acute bacterial meningitis and the frequency of neurologic sequelae among those who survive are high, especially among patients with pneumococcal meningitis.
  • Common Bleeding Disorders
    Hemophilia in Pakistan:
    • A relatively young country, with an ancient past, Pakistan achieved independence from Britain on August 14, 1947, after its bloody partition from India.
    • Pakistan's health care system has crumbled: public hospitals are in appalling condition, even basic treatment unavailable for many common disorders.
    • Private hospitals-modern and fully equipped-foster the only available research, and provide the most advanced and comprehensive care for people with hemophilia, but are extremely expensive and beyond the reach of most.
    • No infrastructure currently exists to provide public and free care to people with this lifelong bleeding disorder.
    • Of the estimated 12,000 people with hemophilia in Pakistan, only 3,100 have been identified.
    • Until early 1980, hemophilia was not even known to exist within the country, and only a few patients were alive. In 1982 the first blood bank was formed.
    • Currently only five major cities-Karachi, Lahore, Rawalpindi-Islamabad, Peshawar Multan, Faisalabad and Quetta-now have facilities to provide plasma or cryo.
    • And treatment at its best in Pakistan is still primitive by Western standards. Virally inactivated high or intermediate purity factor concentrates are available only to the minority elite, who are wealthy enough to pay out of pocket. But the majority of patients, the poor, receive plasma or cryo. They most often receive inferior plasma, which is not always screened for HBV, HCV and HIV.
  • Chronic Obstructive Pulmonary Disease. COPD
    A disease state characterized by airflow limitation that is not fully reversible. Airflow limitation is usually both progressive and associated with an abnormal inflammatory response of the lungs to noxious particles or gases. Symptoms, functional abnormalities, and complications of COPD can all be explained on the basis of this underlying inflammation and the resulting pathology.
  • Chronic Gastric Diseases
    Overview:
    Gastric Causes of Chronic Vomiting
    - Chronic gastritis
    – Lymphocytic/plasmacytic
    – Eosinophilic
    – Associated with GHLOs
    – Parasitic
    – Reflux gastritis
    - Gastric foreign body
    - Gastric ulceration
    - Gastric motility disorders
    - Gastric neoplasia
  • COPD - Chronic Obstructive Pulmonary Disease
    History:
    SOB
    Productive cough
    Recurrent acute chest illnesses
    Exerbation – cold air, foggy weather, atmospheric pollution etc

    Smoking:
    Previous episodes
    Details of previous admissions
    Current treatment
  • Chronic Gastric Diseases
    Overview:
    Gastric Causes of Chronic Vomiting
    - Chronic gastritis
    – Lymphocytic/plasmacytic
    – Eosinophilic
    – Associated with GHLOs
    – Parasitic
    – Reflux gastritis
    - Gastric foreign body
    - Gastric ulceration
    - Gastric motility disorders
    - Gastric neoplasia
  • Chronic Obstructive Pulmonary Disease - COPD
    GOLD Staging Criteria:
    GOLD Staging Criteria
    Stage O: Normal spirometry; chronic sx
    Stage 1 (Mild):
    FEV1> 80%
    Stage 2 (Moderate):
    2A: FEV1 50-80% predicted
    2B: FEV1 30-50% predicted
    Stage 3 (severe):
    FEV1/FVC < 70% AND:
    FEV1 < 30% predicted and clinical evidence of R heart failure
  • Bronchiectasis
    The bronchiectatic cavities may be lined by granulation tissue, squamous epithelium or normal ciliated epithelium. There may also be inflammatory changes in the deeper layers of the bronchial wall and hypertrophy of the bronchial arteries. Chronic inflammatory and fibrotic changes are usually found in the surrounding lung tissue.
  • Sleep Disorder
    Risks and ComplicationsYou have the right to be informed that the surgery may involve risks of unsuccessful results, complications, or injury from both known and unforeseen causes. Because individuals vary in their tissue circulation and healing processes, as well as anesthetic reactions, ultimately there can be no guarantee made as to the results or potential complications. The following complications have been reported in the medical literature.
  • Snoring & Sleep Opnea help?
    The treatments for sleep apnea include weight loss, avoidence of sleep depressants (alcohol, sleeping pills, etc), CPAP ( a mask used at night to keep the airway open), dental repositioning devices, and surgery.
  • Acnezine To Cure All Types of Acne Lesions
    Acne lesions range in severity from comedones (blackheads and whiteheads) to nodules and cysts. Here is a brief definition of acne lesions:
  • Acnezine Can Combat All Types of Acne Scars
    Follicular macular atrophy is more likely to occur on the chest or back of a person with acne. These are small, white, soft lesions, often barely raised above the surface of the skin—somewhat like whiteheads that didn’t fully develop. This condition is sometimes also called "perifollicular elastolysis." The lesions may persist for months to years.
  • Thyroid Problems Cause Hair Loss
    For both ‘men and women’ hair is simply your ‘crowning glory’. People all over the world place a huge deal of ‘social and cultural’ importance on ‘hair and hairstyles’. Most of you never miss your hair, until you start loosing it. That is usually when you enter a ‘mad race’ to find solutions and remedies to regain your ‘crowning glory’. Unfortunately, many conditions such as heavy amounts of stress, diseases, improper hair care and hormonal imbalance result in excessive loss of hair.
  • Hypothyroidism Causes Early Menopause
    Thyroid treatment system i.e. thyromine, works by stimulating the body to produce normal levels of thyroxine, because the supplements are all natural this may be done without side effects such headaches and insomnia. The body is also provided with necessary nutrients that help it to function properly. Thyroid treatment supplements may also help to restore deficient iodine levels, as adequate amounts are vital to a healthy thyroid gland.
  • Heavy Menstrual Periods? Blame It on Your Thyroid
    During heavy menstrual period with severe ache, one more noticeable symptom is the repeated occurrences of ‘hot flashes’, which is sudden feeling of heat in the upper part or all of woman’s body. Face and neck become extremely flushed. Flashes can be as mild as a light instant blush or just very severe enough to wake her from a sound sleep (also called night sweats). Most flashes usually last between 30 seconds and 5 minutes. The most common visible effects are the occurrences of red blotches all over the body.
  • Cigratte Smoking Resposible for 1 of 5 Deaths
    Centers for Disease Control and Prevention. Annual Smoking-Attributable Mortality, Years of Potential Life Lost, and Productivity Losses * U.S., 1997-2001. Morbidity and Mortality Weekly Report (MMWR) 2005; 54(25); 625-628.
  • Suffering From Joint Pain?
    Cartilage is what keeps the bones from grinding against each other. As your immune system eats away at your joint cartilage, pain is brought on by the formation of nerve endings in the affected area. Eventually, the pain is so sever that mobility in those joints is virtually impossible.
  • International organizations of Finance and Trading
    The symptoms of any arthritis start with pain. There is pain in the joints in a way that limits the amount of movement a person has. Now, remember, as well, that arthritis can strike any individual, not necessarily just older people.
  • Hair Loss Prevention
    Benefits of All-Natural Hair Loss Prevention With all-natural Provillus, you will not experience any side effects, unlike those products that use a variety of chemicals as active ingredients. You will also be spared the time, money, and embarrassment that often come with visits to the doctor, since Provillus does not require a prescription. Most importantly, you will get the results you are looking for.
  • The Effectiveness Of Psychological Treatments For Treatment Resistant
    About 30% of people with depression do not respond to an antidepressant at the recommended dose and can be described as having treatment-refractory depression.
  • Effect Of Depression On Glycemic Control In Type Two Diabetes Mellitis
    Nosocomial Transmission is well described in reports from Pakistan, Iraq, Dubai, and South Africa. Available evidence suggests that blood and other body fluids are highly infectious, but simple precautions, such as barrier nursing, effectively prevent secondary transmission.

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